Longitudinal associations of naturalistic psychedelic use with psychotic and manic symptoms.

Psychol Med  – March 31, 2025

Source: PubMed Central

Summary

Contrary to common concerns, people who use psychedelics like psilocybin and LSD don't show increased risk of psychotic or manic symptoms over time. Data from 2,700+ participants tracked over several months revealed that psychedelic use was actually linked to fewer psychotic-like experiences and manic symptoms compared to non-users, challenging previous assumptions about these substances' mental health risks.

Abstract

Longitudinal associations of naturalistic psychedelic use with psychotic and manic symptoms.

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