Elevated Endogenous Psychedelic Bufotenine in the Urine of Patients Diagnosed With a Mental Illness: A Systematic Review.

Cureus  – May 20, 2025

Source: PubMed Central

Summary

Intriguingly, a natural psychedelic compound, bufotenine, is often found at higher levels in individuals with mental health diagnoses. A comprehensive review of existing literature consistently reveals this pattern. This analysis suggests that elevated bufotenine in urine could be a significant indicator, potentially offering new insights into the biological underpinnings of certain mental illnesses. This finding provides valuable direction for understanding brain chemistry.

Abstract

Elevated Endogenous Psychedelic Bufotenine in the Urine of Patients Diagnosed With a Mental Illness: A Systematic Review.

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