The mechanisms of psychedelic therapy
Philosophy of Psychedelics – August 01, 2021
Source: CrossRef
Summary
It's not just brain chemistry: lasting benefits from psychedelic therapy may hinge on profound psychological experiences. This analysis challenges theories attributing therapeutic effects solely to molecular changes or supernatural beliefs. Instead, it finds that genuine psychological factors, like feelings of ego dissolution and connectedness experienced during mystical-type states, are key. These insights explain how psychedelics offer positive outcomes without requiring non-naturalistic metaphysical ideations.
Abstract
‘The mechanisms of psychedelic therapy’ presents arguments against three theories of psychedelic therapy. The Molecular Neuroplasticity Theory ascribes therapeutic benefits to an experience-independent molecular mechanism. This theory is undermined by the correlation between ‘mystical-type experiences’ and beneficial outcomes, which suggests that genuinely psychological mechanisms are involved. The Metaphysical Belief Theory and the Metaphysical Alief Theory fare better on this count: both ascribe beneficial outcomes to the transcendent vision of a ‘Joyous Cosmology’ supposedly encountered in the mystical-type experience. However, these theories struggle to account for the fact that some patients satisfy psychometric criteria for a mystical-type experience without undergoing a non-naturalistic metaphysical hallucination. The psychometric criteria can also be satisfied by more naturalistic experiences of ego dissolution and connectedness. The conclusion is that psychedelics cause lasting benefits via some genuinely psychological factor that (i) correlates with the construct of a mystical-type experience, but (ii) is independent of non-naturalistic metaphysical ideations.