Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact.

Pharmaceuticals (Basel)  – October 23, 2020

Source: PubMed Central

Summary

The human body's intricate processing of natural psychoactive compounds like those in ayahuasca is now better understood. This research aimed to map how key alkaloids (DMT, harmine, etc.) move through and affect the body. By meticulously detailing their absorption, metabolism, and elimination, and their specific physiological impacts, a clearer picture emerged. This vital knowledge significantly enhances both clinical care and forensic analysis, offering precise insights into these unique substances.

Abstract

Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact.

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