Identification of seven psychedelic 2,5-dimethoxy-phenylethyl-amine-based designer drugs via benchtop 1 H nuclear magnetic resonance spectroscopy.
Magnetic resonance in chemistry : MRC – February 01, 2023
Source: PubMed
Summary
Identifying new psychoactive substances (NPS) is a critical challenge, but a new method offers a powerful solution. Researchers successfully analyzed seven phenylethylamine-based designer drugs, including common 2C-X series compounds, using benchtop nmr spectroscopy. This innovative approach, specifically employing 1h nmr, accurately identified these substances. The findings demonstrate the significant potential of benchtop nmr for rapid and accessible drug identification in forensics.
Abstract
The dissemination of spectral information of new psychoactive substances (NPS) acquired on benchtop nuclear magnetic resonance (NMR) spectrometers is of high importance considering the emerging application of such portable and accessible instruments in forensic analyses. Seven members of the 2C-X series (2C-B, 2C-C, 2C-D, 2C-E, 2C-P, 2C-T2, and 2C-T7) of NPS were analyzed via 60 MHz 1 H benchtop NMR spectroscopy and their molecular structural relations are discussed with respect to the observed proton NMR spectra.