Sleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance
NeuroImage August 19, 2011 Jack A. De Havas, Sarayu Parimal, Chun Siong Soon et al. 371 citations
Sleep deprivation reduces functional connectivity within the brain's Default Mode Network and weakens its anti-correlation with the task-positive network. These effects occur both at rest and during a visual attention task, indicating a robust alteration in intrinsic brain network organization. The study involved 26 healthy participants scanned after a normal night of sleep and after about 24 hours of total sleep deprivation.