Ketamine-Augmented Hypnotherapy
Preprints.org June 30, 2026 Dirk Revenstorf, Joost (j.b.c.) Mertens, Martin Schipplick preprint
Ketamine shows antidepressant effects by blocking NMDA receptors and promoting neuroplasticity. Combining it with psychotherapy may enhance treatment for depression, trauma, addiction, and other serious conditions by temporarily disrupting rigid thought patterns and enabling new cognitive and emotional connections. This approach remains experimental and is recommended only after standard treatments fail. The article outlines the neurobiological basis of altered states of consciousness and presents initial clinical experience with ketamine-augmented hypnotherapy (KAHT) as one specific method of ketamine-assisted psychotherapy.