Did the vilca/tobacco snuff combination at Chavín aim for an "ayahuasca effect"?
Proc Natl Acad Sci U S A September 15, 2025 Peter Whitridge
The abstract questions whether the combination of vilca and tobacco snuff used at the ancient Peruvian site of Chavín was intended to produce an effect similar to ayahuasca. It suggests that the specific mixture may have been chosen for its psychoactive properties, possibly to induce altered states of consciousness in ritual contexts. The text does not provide a definitive answer but raises the hypothesis that the blend was designed to mimic or parallel the visionary experiences associated with ayahuasca.