Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens.
Eur Neuropsychopharmacol May 20, 2016 Anna Rickli, Olivier D. Moning, Marius C. Hoener et al. 374 citations
The study compares the receptor interaction profiles of novel psychoactive tryptamines to those of classic hallucinogens. It examines how these substances bind to and activate various serotonin receptors, which are key to their psychoactive effects. The findings indicate that many novel tryptamines have similar receptor activity to classic hallucinogens, but some show distinct profiles that may lead to different subjective effects or risks. This research helps understand the pharmacological basis of these emerging drugs and their potential harms.