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Lubo Zhang

1 paper in the library · 7 citations · publishing 1993

Papers

Lysergic acid diethylamide is a partial agonist at 5-HT2 receptors in ovine uterine artery of late pregnancy

European Journal of Pharmacology January 5, 1993 Lubo Zhang, Donald C. Dyer 7 citations

LSD caused dose-dependent contractions in isolated sheep uterine arteries from late pregnancy, with half-maximal effect at about 18 nM. The maximum contraction was about half that produced by serotonin. LSD also blocked serotonin-induced contractions. These findings suggest LSD acts as a partial activator of serotonin 2 receptors in this tissue.