Performance of schizophrenic patients in the Stroop Color Word Test and electrodermal responsiveness after acute administration of cannabidiol (CBD)
Brazilian Journal of Psychiatry March 1, 2010 Jaime E. C. Hallak, João Paulo Machado‐de‐Sousa, José Alexandre S. Crippa et al. 122 citations
A single dose of cannabidiol (CBD) does not improve selective attention in people with schizophrenia, and higher doses may worsen performance. In a study of 28 patients, those given 600 mg of CBD performed worse on the Stroop Color Word Test than those given 300 mg or placebo, while all groups showed some improvement from practice. No differences were found in electrodermal responses to sounds. The authors suggest that chronic CBD administration might still be beneficial, but acute treatment appears ineffective for cognitive symptoms.