Neurocognitive performance following acute mephedrone administration, with and without alcohol
Journal of Psychopharmacology August 25, 2016 EB de Sousa Fernandes Perna, Esther Papaseit, Clara Pérez‐mañá et al. 26 citations
Mephedrone, a recreational drug similar to MDMA, impairs short-term spatial memory one hour after intake but improves critical tracking performance four hours later. When combined with alcohol, mephedrone reduces reaction time compared to alcohol alone, but does not counteract alcohol's impairing effects on divided attention or spatial memory. Alcohol alone impairs both short- and long-term spatial memory and divided attention. The findings suggest mephedrone enhances psychomotor performance while harming memory, and its stimulatory effects are insufficient to offset alcohol-induced deficits on most cognitive tasks.