Metabolic Fate of Hallucinogenic NBOMes
Chemical Research in Toxicology December 16, 2015 Sebastian Leth‐Petersen, Charlotte Gabel‐Jensen, Nic Gillings et al. 43 citations
The metabolism of the potent psychedelic compound 25B-NBOMe, an illicit drug linked to several fatalities, was studied in pigs and humans. The primary metabolic pathway is 5'-demethylation, followed by conjugation to glucuronic acid. These findings were confirmed by carbon-11 labeling of 25B-NBOMe in three different positions and in vivo evaluation in both species.