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Hiroe T Kamata

1 paper in the library · publishing 2006

Papers

Metabolism of the psychotomimetic tryptamine derivative 5-methoxy-N,N-diisopropyltryptamine in humans: identification and quantification of its urinary metabolites.

Drug metabolism and disposition: the biological fate of chemicals February 1, 2006 Tooru Kamata, Munehiro Katagi, Hiroe T Kamata et al.

The body breaks down the psychedelic drug 5-MeO-DIPT (also known as 'Foxy') through three main pathways: removal of a methyl group to form 5-OH-DIPT, which is then often conjugated; direct addition of a hydroxyl group to the ring, sometimes followed by methylation, producing 6-OH-5-MeO-DIPT; and removal of an isopropyl group to form 5-MeO-NIPT. The first two metabolites are more abundant than the third. The parent drug can still be detected in urine up to 35 hours after use, but no N-oxide form was found.