Associations between MDMA/ecstasy, classic psychedelics, and suicidal thoughts and behaviors in a sample of U.S. adolescents.
Scientific reports December 19, 2022 Grant Jones, Diego Arias, Matthew Nock 18 citations
Lifetime psilocybin use among U.S. adolescents aged 12-17 was associated with 15-23% lower odds of suicidal thinking, planning, and attempts, while LSD use was linked to 20-35% higher odds of these same outcomes. MDMA/ecstasy, peyote, and mescaline showed no significant associations with suicidal thoughts or behaviors. These findings come from a nationally representative sample of 262,617 adolescents surveyed between 2004 and 2019. The results suggest that individual classic psychedelics have distinct relationships with adolescent suicide risk, highlighting the need for further research to clarify these links.