Rates and correlates of cannabis-associated psychotic symptoms in over 230,000 people who use cannabis
Translational Psychiatry September 6, 2022 Tabea Schoeler, Jason Ferris, Adam Winstock 48 citations
About 1 in 200 people who use cannabis (0.47%) experience acute psychotic symptoms—hallucinations or paranoia—severe enough to require emergency medical treatment at some point in their lives, based on data from 233,475 users across multiple countries. Risk is higher among young individuals (2.66 times), those in Denmark (3.01 times), users of high-potency resin (2.11 times), those mixing cannabis with tobacco (2.15 times), and people with pre-existing mental health diagnoses: psychosis (14.01 times), bipolar disorder (4.30 times), anxiety (2.92 times), and depression (2.68 times). The findings suggest certain groups are especially vulnerable to cannabis-induced psychotic symptoms.