Cannabis use is associated with alterations in the midbrain dopamine pathway that is involved in psychosis. The findings suggest a link between cannabis and changes in this brain system, which may help explain the connection between cannabis use and the development of psychotic symptoms.
A review of neuroimaging research on self-referential processing (SRP) distinguishes between verbal and non-verbal forms, each occurring in controlled, top-down tasks (introspection and interoception) and in spontaneous, bottom-up states (mind wandering and body wandering during rest). The authors propose a conceptual and methodological framework for future SRP research, which they apply to understanding psychological and neurological disorders linked to abnormal SRP. The discussion draws on William James' writings on the consciousness of self.