Convergence of Cannabis and Psychosis on the Dopamine System
Jessica Ahrens, Sabrina D. Ford, Betsy Schaefer, David Reese, Ali R. Khan, P. Tibbo, Rachel A Rabin, Clifford M. Cassidy, L. Palaniyappan
JAMA psychiatry April 9, 2025 DOI: 10.1001/jamapsychiatry.2025.0432 via Semantic Scholar
Summary
AI-generated from the abstractCannabis use is associated with alterations in the midbrain dopamine pathway that is involved in psychosis. The findings suggest a link between cannabis and changes in this brain system, which may help explain the connection between cannabis use and the development of psychotic symptoms.
Study at a glance
| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Keywords | Medicine Psychology |
| Key finding | Cannabis use is associated with alterations in the midbrain dopamine pathway involved in psychosis. |
Abstract
This cohort study investigates the association between cannabis and the midbrain dopamine pathway involved in psychosis.