Comparison of Haloperidol and Chlorpromazine in the Treatment of Phencyclidine Psychosis
The Journal of Clinical Pharmacology April 1, 1984 A. James Giannini, Michael S. Eighan, Robert H. Loiselle et al.
Haloperidol and chlorpromazine are both effective for treating phencyclidine (PCP) psychosis, likely by blocking central dopamine receptors. While their effects have been studied extensively in animals and less so in humans, no prior comparison of their relative effects in human populations existed. This study provides that comparison.