The Use of Psychedelics in the Treatment of Medical Conditions: An Analysis of Currently Registered Psychedelics Studies in the American Drug Trial Registry.
Cureus September 1, 2022 Joshua S Kurtz, Neal A Patel, Julian L Gendreau et al. 35 citations
A systematic review of clinicaltrials.gov identified 105 registered clinical trials on psychedelic drugs from 2007 to 2020, with 77.1% starting in 2017 or later. The recent uptrend in psychedelic trials mirrors the overall increase in registered trials. Most studies were early-phase (53.3% phase 1, 25.7% phase 2). Common conditions studied include substance addiction, post-traumatic stress disorder, and major depressive disorder. Potential research gaps were identified, such as studying psychedelics for symptomatic treatment during opioid tapering and for depression that does not respond to selective serotonin reuptake inhibitors.