Cannabinoid Exposure and Subjective Effects of THC and CBD in Edible Cannabis Products.
Cannabis and cannabinoid research February 1, 2024 Laurel P Gibson, Raeghan L Mueller, Evan A Winiger et al.
Regular cannabis users who self-administered commercially available edible products experienced increased intoxication and elation, decreased tension, and no change in paranoia two hours after use. Those who consumed a CBD-dominant product reported less intoxication than those who used a THC-only or THC+CBD product. Participants who used a THC+CBD product consumed less THC and had lower plasma THC levels than those using a THC-only product, yet reported similar positive and psychotomimetic effects. Psychotomimetic effects were very low across all conditions. The findings suggest that edible products containing CBD may allow experienced users to achieve desired effects with lower THC exposure, potentially reducing harm.