Time moving 100-fold slower: time distortion as a diagnostic clue in anti-NMDA receptor encephalitis.
BMC neurology February 24, 2025 Risa Hirata, Hisashi Wada, Kazunori Yamamoto et al. 1 citation
In the early stages of anti-NMDA receptor encephalitis, psychiatric symptoms dominate, making it hard to distinguish from primary psychiatric disorders. Two detailed cases show that pronounced time distortion—specifically the perception of time moving slowly—can be a key early symptom. A middle-aged man experienced time moving 100 times slower, persisting over a year after other symptoms resolved. A young woman reported time moving two to three times slower. Because patients may not spontaneously mention time distortion, actively asking about it during evaluation could aid early diagnosis and treatment of this potentially lethal condition.