Agitation: Neurobiology and current management guidelines.
The American journal of emergency medicine February 1, 2025 Christopher W T Miller, Mario Rullo, Sarah Van Remmen et al. 4 citations
Guidelines for managing agitation in emergency and psychiatric emergency settings have been updated since the 2012 Project BETA recommendations. This paper synthesizes current guidelines, explains the neurobiology of agitation, and links brain mechanisms to the pharmacological profiles of recommended drugs, including ketamine and droperidol, which have seen increased use. Clinicians are given treatment strategies tailored to specific causes of agitation.