Improvement in pain by using lidocaine combined with esketamine in elderly patients receiving local anaesthesia for percutaneous kyphoplasty: a randomized controlled study.
BMC anesthesiology October 23, 2024 Longyuan Zhou, Lei Lv, Ruilan Wu et al. 4 citations
Adding esketamine to lidocaine during local anaesthesia for percutaneous kyphoplasty in elderly patients reduces pain and improves safety and comfort. In a trial of 66 patients aged 60–80, those receiving lidocaine plus esketamine reported lower pain scores during needle insertion, balloon dilation, cement injection, and after surgery compared with those receiving lidocaine alone. Blood pressure and heart rate were more stable, sedation scores were lower, and patient satisfaction reached 100% in the combination group versus 48% in the lidocaine-only group. No complications occurred in either group.