Characterization of Oral Ketamine Use: A Retrospective Review.
Journal of pain & palliative care pharmacotherapy March 1, 2025 Miranda Hetrick, Emily Casey, Jacob Radcliff et al. 2 citations
Oral ketamine was administered safely for pain control in hospitalized patients, with a low incidence of safety events. The median starting dose was 1 mg/kg/day and the median maximum dose was 1.6 mg/kg/day. Median oral morphine equivalent doses decreased from the first to the last day of therapy. The study population included adults at a large academic hospital, many of whom may have had high opioid tolerance or opioid-induced hyperalgesia. The findings suggest oral ketamine is a safe analgesic option, though further research on efficacy and safety is needed.