Determination of Arylcyclohexylamines in Biological Specimens: Sensors and Sample Pre-Treatment Approaches.
Micromachines July 30, 2024 Rodrigo Pelixo, Mário Barroso, Eugenia Gallardo et al. 1 citation
Arylcyclohexylamines (ACHs) are a major group of new psychoactive substances used recreationally and in drug-facilitated sexual assault, with ketamine consumption remaining notably high. This review covers recent laboratory strategies for identifying and quantifying ACH compounds, including phencyclidine, ketamine, and eticyclidine analogues, using traditional analytical techniques and emerging point-of-care sensor technology. The review highlights the consistent need for higher sensitivity in analyzing real-case samples and simulated matrices, and emphasizes ongoing research to develop more sensitive, faster, and more capable sensors.