Therapeutic Potential of Intravenous Ketamine in Early-Onset Dementia: A Case Report.
Cureus July 1, 2024 Mariam Tadros, Dianella Rente Lavastida, Ashraf Hanna 2 citations
A 56-year-old woman with early-onset dementia who had not responded to standard treatments including memantine, donepezil, and rivastigmine received a series of intravenous ketamine infusions over two months. After treatment, she experienced notable improvements in cognitive function, mood, and daily living activities, reporting more mental clarity, increased focus, improved memory, and increased energy. This case suggests that IV ketamine may be a potential therapeutic option for early-onset dementia, but larger clinical trials are needed to confirm these findings.