Department of Pharmacology, Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan; Department of Drug Dependence Research, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan; Laboratory of Pharmacotherapeutics, Faculty of Pharmaceutical Science, Tokyo University of Science, Tokyo, Japan.
1 paper in the library · 1 citation · publishing 2024
In Japan, more people are misusing the over-the-counter drug dextromethorphan (DXM), often to cope with severe trauma-related and mood symptoms. These patients have substance use disorders and self-medicate with DXM. Because ketamine has similar psychopharmacological effects to DXM, the authors propose that ketamine could serve as an alternative pharmacological treatment for these patients.