Ketamine in Substance Use Disorder Treatment: A Narrative Review.
Alpha psychiatry March 1, 2024 Anna Famuła, Jakub Radoszewski, Tomasz Czerwiec et al. 8 citations
Ketamine, long used as an anesthetic, is being investigated as a treatment for substance use disorder (SUD). This narrative review examines how ketamine may work through effects on glutamate signaling, neuroplasticity, and reward pathways. The psychotropic and dissociative properties of ketamine are considered for their role in therapeutic outcomes and patient experience. The review calls for more research to understand ketamine's potential and to develop personalized addiction treatments.