Efficient magnetic solid-phase extraction, UPLC-MS/MS detection, and consumption assessment of five trace psychoactive substances.
Environmental science and pollution research international May 1, 2024 Rong Zhu, Shurui Cao, Hongtao Su et al. 3 citations
A magnetic shrimp shell biochar-based adsorbent was synthesized and used to extract trace psychoactive substances from municipal wastewater. The adsorbent showed good pH stability, anti-interference properties, fast magnetic separation, reusability, and reproducibility. A method combining magnetic solid-phase extraction with ultra-high-performance liquid chromatography-tandem mass spectrometry was developed and validated for quantifying five psychoactive substances in real wastewater samples. The method achieved low detection limits (1.00-4.75 ng/L) and high precision. Applying the method to wastewater from Chongqing revealed that methamphetamine and 3,4-methylenedioxymethamphetamine were the prevalent illegal drugs. MDMA concentrations and per capita consumption changed between July and September, but no weekly differences were observed.