Exploring Self-Reported Effects of Naturalistic Psychedelic Use Among Gender and Sexual Minorities: A Quantitative Survey Study.
Journal of psychoactive drugs June 18, 2025 Rafaelle Lancelotta, Meghan DellaCrosse, Diana Quinn et al. 7 citations
Among 346 LGBTQIA+ individuals, mostly White and in their early 30s, those who used psychedelics reported improvements in mental health and shifts in gender and sexual identity. Retrospective reports showed large reductions in traumatic stress, depression, and anxiety, along with increased psychological flexibility. A significant link emerged between the intensity of the psychedelic experience and greater self-acceptance and sexual identity exploration. Most participants (77%) saw therapeutic potential in psychedelics for gender dysphoria, and 65% reported changes in gender identity attitudes after use. The findings suggest psychedelics may support identity exploration and mental health in this population, warranting further research.