No evidence that LSD microdosing affects recall or the balance between distracter resistance and updating
bioRxiv Preprint Server December 2, 2021 Sean James Fallon 2 citations preprint
In a randomized double-blind, placebo-controlled study, three different low doses of LSD (5 μg, 10 μg, and 20 μg) were tested for their effects on working memory in a modified delay-match-to-sample task that required ignoring or updating novel items. There was no evidence that any of the LSD microdoses affected the accuracy or efficiency of working memory recall, nor was there evidence for differential effects on ignoring or updating. These results are preliminary due to the small sample size, and larger studies are required to establish whether LSD microdoses affect short-term recall.