Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells
bioRxiv Preprint Server February 14, 2024 Anne S. Fleiner, Daniel Kolnier, Nicholas Hagger-Vaughan et al. preprint
Propofol and ketamine are both general anaesthetics but produce markedly different states of consciousness. Propofol induces a deeply unconscious state with few or no dream reports, whereas ketamine anaesthesia is frequently followed by reports of vivid dreams. The abstract contrasts these two drugs' effects on awareness and dreaming, highlighting that different anaesthetics can produce distinct subjective experiences even when both cause loss of consciousness.