PloS one
January 1, 2023
Marco Schlosser, Harriet Demnitz-King, Thorsten Barnhofer et al.
13 citations
Older adults with subjective cognitive decline (SCD) recruited from memory clinics are at higher risk for dementia and often have reduced well-being due to memory concerns and fear of dementia. A randomized trial compared an 8-week caring mindfulness-based approach for seniors (CMBAS) with a health self-management program (HSMP) in 147 participants. The mindfulness program showed a small advantage over HSMP in improving a sense of connection immediately after the intervention. However, overall psychological well-being, quality of life, and other composite measures did not increase in either group. The findings suggest that these brief non-pharmacological interventions had only limited effects on well-being in SCD.
PloS one
January 1, 2023
Marco Schlosser, Olga M Klimecki, Fabienne Collette et al.
6 citations
An 18-month meditation training program for healthy older adults aged 65 to 84 improved a composite measure of well-being encompassing awareness, connection, and insight, compared to an active control of English language training. The meditation group also showed significant increases in psychological quality of life, awareness, insight, and the global score from the start to the end of the study. However, meditation did not outperform the active control on the Psychological Well-being Scale total score, and improvements in psychological quality of life were no longer significant after adjusting for multiple comparisons. The trial, involving 137 participants, represents the longest randomized meditation training study to date.
April 8, 2024
Saampras Ganesan, Aki Tsuchiyagaito, Greg J. Siegle et al.
2 citations
preprint
Meditation practices, which have been adapted into manualized interventions for conditions like depression, pain, addiction, and anxiety, show therapeutic promise, but their neuroscientific basis remains unclear. Current neuroimaging studies rely on small, heterogeneous datasets that vary in practice types, participant experience, clinical targets, and imaging methods, limiting generalizability and replicability. To address this, the ENIGMA-Meditation consortium was formed as a global collaboration to conduct systematic meta- and mega-analyses of distributed neuroimaging data using standardized methods. This framework aims to improve statistical power and rigorously characterize the neural mechanisms underlying meditation's effects on psychological and cognitive attributes, advancing the field of contemplative neuroscience.