[Subanesthetic Dose Ketamine Infusions for Treatment-Resistant Major Depression: An Application Protocol at a Public Hospital in Argentina].
Vertex (Buenos Aires, Argentina) July 10, 2025 Micaela Dines, Adriana Bulacia, Paloma Bamondez et al.
Intravenous ketamine at subanesthetic doses offers rapid relief for depressive and suicidal symptoms in treatment-resistant major depression. A protocol for administering ketamine infusions in a general hospital, based on international guidelines, specifies inclusion and exclusion criteria, dosage, administration procedures, and patient monitoring. The protocol also addresses adverse effects and safety considerations, aiming to optimize ketamine's efficacy and safety for treatment-resistant depression.