Efficacy and safety of esketamine hydrochloride injection at different dosages for patients undergoing radical thyroidectomy for thyroid cancer: a randomized trial.
BMC anesthesiology July 1, 2025 Yihuan Luo, Hua Fang 1 citation
In patients undergoing thyroid surgery, adding esketamine to the anesthetic regimen improves recovery quality, reduces pain and coughing, and maintains stable blood pressure and heart rate. A dose of 0.25 mg/kg provides the best balance of benefits and faster recovery compared to 0.35 mg/kg. Both doses lowered pain scores and anxiety and depression scores after surgery.