The Potential Role of Psilocybin in Traumatic Brain Injury Recovery: A Narrative Review
Brain Sciences May 26, 2025 Charles Palmer, Ally T Ferber, Brian D Greenwald 4 citations
A narrative review of the literature suggests that psilocybin-assisted therapy may benefit people with traumatic brain injury by reducing inflammation, promoting neuroplasticity and neuroregeneration, and alleviating associated mood disorders. The review examined 29 articles from 2000–2025, plus additional references, and notes that positive findings in related fields—such as treatment for depression and addiction—highlight the need for more extensive clinical trials on psilocybin's role in TBI recovery.