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Lino Nobili

4 papers in the library · 159 citations · publishing 2017-2026

Papers

Global and local complexity of intracranial EEG decreases during NREM sleep

Neuroscience of Consciousness January 27, 2017 Michael Schartner, Andrea Pigorini, Steve A. Gibbs et al. 158 citations

During non-rapid eye movement (NREM) sleep, neural dynamical complexity—measured by Lempel-Ziv complexity, amplitude coalition entropy, and synchrony coalition entropy—decreased substantially across broadly distributed brain regions in ten epilepsy patients. This decrease partially reversed during late-night NREM sleep and returned to wakeful rest levels during rapid eye movement (REM) sleep. Local brain regions mirrored this global pattern. The frontal lobe showed elevated signal complexity. These changes were not solely due to spectral power differences. The findings suggest that level of consciousness correlates with neural dynamical complexity.

Inducing unusual bodily sensations and out-of-body experiences across the wake-sleep cycle: a high-density EEG and neurophenomenology study

PsyArXiv April 13, 2025 Teresa Campillo-Ferrer, Antonella Iadarola, Ramona Cordani et al. 1 citation preprint

During the transition from wakefulness to sleep, unusual bodily sensations and out-of-body experiences can be induced. A high-density EEG and neurophenomenology approach reveals specific brain activity patterns associated with these phenomena, suggesting that the brain's altered state during sleep onset may facilitate such experiences.

Facilitating unusual bodily experiences and out-of-body experiences across wakefulness and sleep: A high-density EEG and neurophenomenology study

Consciousness and Cognition February 11, 2026 Teresa Campillo-Ferrer, Antonella Iadarola, Ramona Cordani et al.

Unusual bodily experiences (UBEs)—illusory perceptions such as floating, body distortions, or out-of-body sensations—can occur during meditation and sleep. In a controlled sleep laboratory, 20 of 35 healthy participants reported 36 UBEs, primarily during meditation (wakefulness) but also during arousals, REM sleep, and non-REM sleep. Electroencephalography (EEG) analyses revealed that UBEs emerge during intermediate states of consciousness that combine features of wakefulness and sleep. Specifically, UBEs were associated with EEG reactivation: increased high-frequency activity (beta and gamma) and decreased low-frequency activity (delta and theta), especially around temporal regions. These findings offer new insights into the neural correlates of self-consciousness and body perception across sleep and wakefulness.

Statistical diversity distinguishes global states of consciousness

bioRxiv December 7, 2023 Joseph Starkey, Robin L. Carhart-Harris, Andrea Pigorini et al. preprint

A measure of 'statistical complexity' that calculates the diversity of statistical interactions in neural activity, removing randomness, was tested on human brain data from different sleep stages and from people under ketamine, LSD, and psilocybin. Statistical complexity differentiated sleep stages similarly to the standard Lempel-Ziv complexity measure and increased relative to placebo for all three psychedelic substances. The measure is a useful alternative for investigating neural activity complexity across states of consciousness.