Department of Anesthesiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, China. Zhangmin201609@outlook.com.
2 papers in the library · 4 citations · publishing 2024-2026
Patients who undergo percutaneous coronary intervention (PCI) for coronary heart disease often suffer from depression, anxiety, sleep problems, poor medication adherence, and physical symptoms, which can raise their risk of further cardiovascular events. Mindfulness-based stress reduction (MBSR), a mind-body therapy, has shown promising results in helping these patients recover. This article reviews the application of MBSR in post-PCI patients and discusses its future potential.
Adding low-dose esketamine (1 mg/kg) to sufentanil patient-controlled analgesia (PCA) significantly reduces postoperative depression and anxiety in elderly colorectal cancer patients without improving pain control or increasing side effects. In a double-blind trial of 99 patients aged 65 and older, those receiving esketamine had lower anxiety and depression scores at 24 and 72 hours after surgery compared to those given only sufentanil; no dose-dependent difference was seen between 1 mg/kg and 2 mg/kg esketamine. Pain scores and need for rescue analgesia did not differ between groups. Patient satisfaction was higher with esketamine (77% and 90%) than with sufentanil alone (50%). Adverse events were similar across groups.