Changes in functional connectivity preserve scale-free neuronal and behavioral dynamics
Physical review. E November 2, 2023 Anja Rabus, Davor Curic, Victorita E. Ivan et al. 8 citations
The brain may maintain optimal information transmission even when its functional connectivity is drastically altered. The psychedelic compound ibogaine, which induces an altered state of consciousness, fundamentally changes functional connectivity in the retrosplenial cortex of mice. Despite these changes, the scale-free statistics of movement and of neuronal avalanches among behaviorally related neurons remain largely unaltered. This suggests that the propagation of information within biological neural networks is robust to changes in the functional organization of neuronal subpopulations, offering a new perspective on how adaptive functional networks may support optimal information transmission.