Rapid Detection and Quantification of Hallucinogenic Salvinorin A in Commercial Salvia divinorum Products by DART-HRMS.
ACS omega January 10, 2023 Megan I Chambers, Justine E Giffen-Lemieux, Rabi A Musah 5 citations
A direct analysis in real time-high-resolution mass spectrometry (DART-HRMS) method rapidly screens and quantifies salvinorin A in Salvia divinorum plant material without lengthy sample pretreatment. Raw Salvia leaves contained an average of 1.54 mg/g of salvinorin A, while enhanced leaf extracts had between 13.0 and 53.2 mg/g. Cholesterol served as a suitable internal standard for quantification. The approach bypasses traditional chromatographic sample preparation, enabling faster assessment of psychoactive plant materials.