2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOME): A Harmful Hallucinogen Review.
Journal of analytical toxicology January 21, 2021 Katarzyna Kamińska, Paweł Świt, Kamilla Malek 9 citations
25I-NBOMe, a synthetic hallucinogen chemically related to mescaline and sold online as a legal alternative to LSD, acts as a potent serotonin 5-HT2A receptor agonist. Knowledge of its pharmacological properties remains limited, with few published in vivo and in vitro studies. A 2016 critical review reported 51 non-fatal intoxications and 21 deaths across Europe. Case reports describe toxic effects including tachycardia, hypertension, hallucinations, rhabdomyolysis, acute kidney injury, and death. The growing number of fatal and non-fatal intoxication cases indicates 25I-NBOMe poses a serious public health danger.