A single ibogaine treatment reduced opioid withdrawal symptoms and led to opioid cessation or sustained reduced use over 12 months in dependent individuals. Among 14 participants (50% female) receiving legal ibogaine treatment in New Zealand, addiction severity scores dropped significantly from baseline to 12-month follow-up for the 8 who completed all interviews. Depression scores also significantly decreased. Opioid withdrawal symptoms fell acutely after treatment for all 14 participants. One patient died during treatment. Legal availability in New Zealand may improve outcomes by allowing treatment providers to collaborate with other health professionals.
Most TikTok videos about MDMA portray the drug neutrally (40.6%) or positively (34.9%), with intoxication presumed in 40.2% of videos. Humor was the most common theme (80.5%). Only nine out of 498 videos contained harm reduction content, which together were viewed nearly one million times. The findings suggest that unrestricted access to MDMA-related content on TikTok may shape perceptions of the drug, and better monitoring or promotion of harm reduction material could help offset potential harms.