Characterization of hallucinogenic phenethylamines using high-resolution mass spectrometry for non-targeted screening purposes.
Drug testing and analysis October 1, 2017 Daniel Pasin, Adam Cawley, Sergei Bidny et al. 25 citations
Twelve 2C-X, six DOX, and fourteen 25X-NBOMe hallucinogenic phenethylamines, including two deuterated derivatives, were analyzed using UPLC-QTOF-MS with collision-induced dissociation at 10, 20, and 40 eV. Common neutral and radical losses (e.g., NH3, •CH6N, C2H7N, C2H9N) and characteristic product ions were identified for each class. Novel analogues can be detected by applying neutral loss filters and extracting these common product ions, enabling detection of rapidly changing new psychoactive substances without targeted screening.