Subjective effects of Salvia divinorum: LSD- or marijuana-like?
Journal of psychoactive drugs September 1, 2009 Dawn N Albertson, Laura E Grubbs 29 citations
Salvia divinorum, a naturally occurring psychedelic and potent hallucinogen, acts via a unique molecular mechanism as a kappa opioid receptor agonist. A survey of 193 participants, including 34 Salvia users, found that users differed from nonusers in personality characteristics and reported consuming significantly more alcohol. Although users rated their hallucinogenic experiences as similar to previously published reports, the majority likened the experience to marijuana rather than traditional psychedelics. Low scores on the ARCI LSD subscale confirmed this finding and challenge the prevailing theory that Salvia produces LSD-like subjective effects.