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Akinori Miyashita

1 paper in the library · 15 citations · publishing 2009

Papers

[Chemical and DNA analyses for the products of a psychoactive plant, Voacanga africana].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan August 1, 2009 Ruri Kikura-Hanajiri, Takuro Maruyama, Akinori Miyashita et al. 15 citations

Products sold as Voacanga africana, a tree whose bark and seeds contain psychoactive alkaloids, fall into two chemical types: ibogaine-type (0.05–0.6% ibogaine plus voacamine, voacamidine, and voacangine) and tabersonine-type (0.6–1.6% tabersonine). DNA analysis of the chloroplast trnL-F region showed most products came from V. africana or closely related plants, with four distinct genotypes. The study developed a simultaneous LC/MS method to quantify these alkaloids and used DNA barcoding to verify botanical origins, providing tools to monitor the distribution of this non-controlled psychotropic plant.