Simultaneous determination of 11 designated hallucinogenic phenethylamines by ultra-fast liquid chromatography with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences October 1, 2008 Jun Zhe Min, Yoshiha Shimizu, Toshimasa Toyo'Oka et al. 17 citations
A new method using ultra-fast liquid chromatography with fluorescence detection (UFLC-FL) was developed to simultaneously identify and measure 11 phenethylamine-type drugs. The drugs were chemically labeled and separated on a specialized column, with detection limits ranging from 10 femtomoles to 2.5 picomoles. The method showed good accuracy and precision. When applied to real products from the Japanese market, it identified and quantified BDB (0.24 mg/mg), MMDA-2 (0.98 mg/mL), and 2C-I (0.016 mg/mg) in powder, liquid, and mushroom-like samples. The procedure is simple, selective, and sensitive, making it useful for analyzing these designated drugs in various samples, including biological specimens.