Simultaneous determination of thirteen plant alkaloids in a human specimen by SPE and HPLC.
Journal of separation science July 1, 2008 Jörg Pietsch, Jana Günther, Thomas Henle et al. 56 citations
A new screening method using solid-phase extraction and liquid chromatography with photodiode array detection can simultaneously identify and quantify thirteen plant alkaloids in human samples. The validated technique provides selective, accurate, and sensitive measurements of these compounds, which include both toxic and medicinal substances. Analysis of forensic and clinical specimens demonstrates the method's usefulness for detecting intoxications, monitoring drug abuse, and checking patient compliance with prescribed medications.