Classic Psychedelics for the Treatment of Depression: Potential Benefits and Challenges.
Drugs May 1, 2025 Sharmin Ghaznavi, Sarah G Richter 6 citations
Recent research has revived interest in psychedelics as treatments for depression. This review examines studies on psilocybin, ayahuasca, DMT, and 5-Me-O DMT for treatment-resistant and major depression. It discusses the potential to expand depression treatment options based on available data, while also highlighting the difficulties and limitations of psychedelic research that complicate assessment of that potential.