Identification of 2,5-dimethoxy-4-ethylthiophenethylamine and its metabolites in the urine of rats by gas chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences December 25, 2003 Li-Chan Lin, Ju-Tsung Liu, Shiu-Huey Chou et al. 29 citations
A gas chromatography-mass spectrometry method identified four metabolites of the psychoactive compound 2C-T-2 in rat urine after a single 20 mg/kg dose. The metabolites included 2-(4-ethylthio-2,5-dimethoxyphenyl)-ethanol, 4-ethylthio-2,5-dimethoxyphenyl acetic acid, and two isomeric acetamido metabolites. Based on these findings, a metabolic pathway for 2C-T-2 in rats is proposed.